Leucovorin (leucovorin calcium) is one of several active, chemically reduced derivatives of folic acid. It is useful as an antidote to drugs which act as folic acid antagonists.
What is Leucovorin injection?
Leucovorin injection is the class of medications called folic acid analogs. Mostly used to treat people who are receiving methotrexate by protecting healthy cells.
Leucovorin injection uses
- This medication is used in the treatment of various types of cancers of
- Overdose of Methotrexate And its Side Effects
- Colorectal Cancer
How does Leucovorin injection works?
It works similar to folic acid(vitamin). It is given with Fluorouracil or Methotrexate and helps in binding fluorouracil to an enzyme inside cancer cells which leads to a longer stay of fluorouracil in cells and its anticancer activity. For methotrexate, it works as a source of folic acid.
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